Biocomputronics

We're using computers to design biological devices from genetic parts. These devices will help solve interesting and important problems.

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Research

Synthetic biology is a relatively new discipline based on the concept of viewing living cells as machines that can be engineered the same way as we see in electronics or mechanics.

The engineering is based on combining genetic parts (those found in nature as well as new synthetic parts) into biological devices to achieve new functions, new products or repair what is broken (diseases).

This allows us to tap into the diversity of nature and biological solutions based on billions of years of evolution and combine them to design biological solutions for current and future challenges. Synthetic biology has the potential to be a transforming technology for our society, and we are only limited by our own imaginations.

We use our imagination to dream up an idea. Then we use computers to help us turn that idea into a design, and ultimately a DNA sequence that encodes the design. Once we have a DNA sequence to encode the new biological device, we can synthesize that DNA and put it into a cell or an organism to achieve our goal.

Collaborations

We are currently looking for collaborators. We have ideas and designs in the works, but we need to collaborate with scientists that have the laboratory infrastructure to reduce our designs to practice.

We currently have a nearly complete design for a system in the biotherapeutics manufacturing space. We want to engineer the Chinese Hamster Ovary (CHO) cell line in a way that will ensure the transgenic sequence being expressed will remain stable permanently. The loss or silencing of the transgene sequence leads to cell suicide, guaranteeing a stably expressing population of cells over time.

We have other ideas cooking as well. We'll post them here once they are more thought out. If you have ideas and would like to collaborate on setting them in motion, please reach out to us.

Example Device